1  Yanyun Zhu, Gonghua Song*, Peng Lu, Mingjie Zhu, Yilang Chen.Convenient Synthesis of Novel 2-Substituted Imidazopyrazinone Derivatives. Syn. Comm., 2012, 42, 469–479. 

2  Huangdi Feng, Yuan Li, Erik V. Van der Eycken, Yanqing Peng, Gonghua Song*. Synthesis of polysubstituted pyridines under combined microwave and ultrasound irradiation: K2CO3-promoted tandem addition/cyclization/hydrogen shift process.Tetrahedron Lett., 2012, 53, 1160–1162.

3  Huangdi Feng, Shengjie Lin, Jiayi Wang, Gonghua Song*, Yanqing Peng. Aqueous heterogeneous synthesis of polysubstituted 2,6-dicyanoanilines via combined microwave and ultrasound-assisted multicomponent reaction. Green Process. Synth.  2012, 1,463–468. 

4  Guanyi Jin, Jian Zhang, Dan Fu, Jingjing Wu, Song Cao*.One-Pot, Three-Component Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles Starting from Primary Alcohols. Eur J Org Chem, 2012, 5446-5449.

5  Jian Zhang, Jingjing Wu, Yang Xiong, Song Cao*. Synthesis of unsymmetrical biaryl ethers through nickel-promoted coupling of polyfluoroarenes with arylboronic acids and oxygen.  Chem Commun, 2012, 48, 8553-8555. 

6  Lixia Yin, Jingjing Wu, Juan Xiao, Song Cao*. Oxidation of benzylic methylenes to ketones with Oxone-KBr in aqueous acetonitrile under transition metal free conditions.    Tetrahedron Letters ,2012, 53, 4418-4421.

7  Mingxi Wu, Wenwen Zhao, Guanyi Jin, Qingchun Huang, Song Cao*. Synthesis and Insecticidal Activities of Novel Analogues of Flubendiamide Containing a Hexafluoroisopropanol Moiety. Chin J Chem, 2012, 30, 1310-1314. 

8  Wenwen Zhao, Jingjing Wu, Song Cao*.Highly efficient NiCl2/NiCl2(PCy3)2 co-catalyzed hydrodefluorination of fluoroarenes and trifluorotoluenes with superhydride. Adv Synth Catal, 2012, 354(4), 574-578  6.048 

9 Jingjing Wu, Wenwen Zhao, Song Cao*.Synthesis of Difluoromethyl-Containing α-Acyloxycarboxamide Derivatives through a Passerini Reaction and Desulfonylation.    Eur J Org Chem, 2012, 1380–1387. 

10  Chen,,Xi-Bo;Hu,Qiu-Peng;Yuan,Qian-Jia;Ding,Wei;Ren,iangmeng;Zeng,Bu-Bing.

Simultaneous dehalogenation and hydrogenation reduction of halogen-heteroaromatic aldehydes. Tetrahedron Letters, 2012.

11  Zheng Xu, Lin Xu, Ji Zhou, Yufang Xu, Weiping Zhu and Xuhong Qian.A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells.    Chem. Commun., 2012,48,10871-10873.

12 Qingshan Du, Weiping Zhu, Zhenjiang Zhao, Xuhong Qian, and Yufang Xu. Novel Benzo-1,2,3-thiadiazole-7-carboxylate Derivatives As Plant Activators and the Development of Their Agricultural Applications. J. Agric.Food Chem , 2012,60, 346-353.

13  Yu Zhang, Xiangfeng Guo, Lihua Jia, Shicheng Xu, Zhihui Xu, Libo Zheng, Xuhong Qian. Substituent-dependent fluorescent sensors for zinc ions based on carboxamidoquinoline    Dalton Trans., 2012,41,11776-11782.

14  Xiaojun Zhang, Yufang Xu, Peng Guo, Xuhong Qian. A dual channel chemodosimeter for Hg2+ and Ag+ using a 1,3-dithiane modified BODIPY. N. J. Chem 2012,36,1621-1625. 

15 Xiaojun Zhang, Eric V. Anslyn, Xuhong Qian. Discrimination of vicinal-diol-containing flavonoids and black teas by arrays of host-indicator ensembles. Supramol. Chem., 2012,24,520-525.

16  Xiaojun Zhang, Lei You, Eric V. Anslyn, Xuhong Qian.Discrimination and Classification of Ginsenosides and Ginsengs Using Bis-Boronic Acid Receptors in Dynamic Multicomponent Indicator Displacement Sensor Arrays. Chem. Eur. J. 2012,18,1102-1110. 

17  Lin Xu, Yufang Xu, Weiping Zhu, Zheng Xu, Mengjie Chen, Xuhong Qian. Fluorescence sensing of iodide and bromide in aqueous solution: anion ligand exchanging and metal ion removing. New J. Chem 2012,36,1435-1438. 

18  Mengzhu Xue, Jun Yuan, Bin Wu, Xue Zhao, Xiaofeng Liu, Jin Huang, Zhenjiang Zhao, Honglin Li, Yufang Xu.Novel inhibitors for p90 ribosomal S6 protein kinase 2: design, synthesis and SAR. Journal of Chinese Pharmaceutical Sciences, 201221401-408.

19  Yanyan Diao, Weiqiang Lu, Huangtao Jin, Junsheng Zhu, Le Han, Minghao Xu, Rui Gao, Xu Shen, Zhenjiang Zhao, Xiaofeng Liu, Yufang Xu, Jin Huang, and Honglin Li.  Discovery of Diverse Human Dihydroorotate Dehydrogenase Inhibitors as mmunosuppressive Agents by Structure-Based Virtual Screening. J. Med. Chem. 2012558341-8349. 

20  Mengzhu Xue, Minghao Xu, Weiqiang Lu, Jin Huang, Honglin Li, Yufang Xu, Xiaofeng Liu, and Zhenjiang Zhao. Synthesis, activity evaluation, and docking analysis of barbituric acid aryl hydrazone derivatives as RSK2 inhibitors.  J. Enzym. Inhib.Med. Chem. 2012ASAP. 

21  Lin Xu, Yufang Xu, Weiping Zhu, Chunmei Yang, Le Han and Xuhong Qian. A highly selective and sensitive fluorescence “turn-on” probe for Ag+ in aqueous solution and live cells. Dalton Trans. , 2012,41,7212-7217.

22  Shenyi Zhang, Chunmei Yang, Weiping Zhu, Bubing Zeng, Youjun Yang, Yufang Xu and Xuhong Qian. Highly selective, naked-eye and fluorescent “off-on” probe for detection of histidine/histidine-rich proteins and its application in living cell imaging. Org. Bio. Chem.,  2012,10,1653-1658.

23  Mengjie Chen, Chusen Huang, Chunsheng He, Weiping Zhu, Yufang Xu, and Yunfeng Lu.  Glucose-Responsive Controlled Release System Using Glucose Oxidase-Gated Mesoporous Silica Nanocontainers . Chem. Commun. , 2012,48,9522-9524.

24  Liyan Yin, Chunsheng He, Chusen Huang, Weiping Zhu, Xin Wang, Yufang Xu and Xuhong Qian.A pH and Temperature Dual Responsive Polymeric Fluorescent Sensor and Its Imaging in Living Cells. Chem. Commun., 2012484486-4488. 

25  Lu, W.; Zhao, X.; Zou, S.; Huang, J*.A fluorimetric assay for human reticulocyte 15-lipoxygenase-1 activity. Analytical Biochemistry. 2012,426: 66–68.

26  Yichun Xu, Zijing Jiang, Peihao Yin, Qi Li, Jianwen Liu*.Role for Class I histone deacetylases in multidrug resistance. Exp Cell Res, 2012,318 :117-186.

27  Ke Shen,1 Daling Cui,1 Liyun Sun,1 Yanhua Lu,1 Mingquan Han, and Jianwen Liu*.  Inhibition of IGF-IR Increases Chemosensitivity in Human Colorectal Cancer Cells Through MRP-2 Promoter Suppression.  J Cell Biochem, 2012,113:2086–2097.

28  Yuanhong Zheng & Vanminh Le & Zhuoan Cheng & Sheng Xie & Hegeng Li & Jianhui Tian & Jianwen Liu*. Development of rapid and highly sensitive HSPA1A promoter-driven luciferase reporter system for assessing oxidative stress associated with low-dose photodynamic therapy. Cell Stress and Chaperones, 2012.

28  Chaoqian Cai, Jiayu Gong, Xiaofeng Liu,Hualiang Jiang,Daqi Gao,Honglin Li. A novel, customizable and optimizable parameter method using spherical harmonics for molecular shape similarity comparisons. J Mol Model, 2012,18(4):1597-610.

29  Fang Bai, Hongyan Liu,Linjiang Tong, Wei Zhou, Li Liu, Zhenjiang Zhao, Xiaofeng Liu,Hualiang Jiang, Xicheng Wang, Hua Xie, Honglin Li*. Discovery of novel selective inhibitors for EGFR-T790M L858R. Bioorganic & Medicinal Chemistry Letters  2012,22: 1365–1370.

30  Quanjuan Zhang, Zhichuan Zhu, Yongli Zheng, Jiagao Cheng, Na Zhang, Yi-Tao Long, Jing Zheng*, Xuhong Qian*, Youjun Yang*.A Three-Channel Fluorescent Probe That Distinguishes Peroxynitrite from Hypochlorite. J. Am. Chem. Soc.,2012, 134, 18479-81842. 

31 Liwei Zhao, Jianfeng Li, Yiquan Li, Jianwen Liu, Thomas Wirth, Zhong Li*. Selenium-containing Naphthalimides as Anticancer Agents: Design, Synthesis and Bioactivity.  Bioorg. Med. Chem., 2012, 20(8), 2558-2563.

32  Baozhu Wang, Jiagao Cheng, Zhiping Xu, Xiaoyong Xu, Xusheng Shao, Zhong Li*. Synthesis and Biological Activity Evaluation of Novel β-Substituted Nitromethylene Neonicotinoid Analogues. Molecules,2012, 17, 10014-10025.

33  Chao Li, Xiao-Yong Xu, Xuan-Qi Liu, Qiu-Guo Fu, Wei Wang, Qing-Fu Ye, Zhong Li*.An overview of radio or stable isotope-labeled cis-neonicotinoid analogs. J. Label Compd. Rad., 2012, 55, 339-345.

34  Baozhu Wang, Shaoyong Ke, Babu Kishore, Xiaoyong Xu, Zhuyan Zou, Zhong Li*.  Synthetic Commun.A Facile Synthesis of Pyrimidone Derivatives and Single-Crystal Characterization of Pymetrozine, 2012, 42(16), 2327-2336. 

35  Siyuan Lu, Xusheng Shao, Zhong Li, Zhiping Xu*, Shishuai Zhao, Yingli Wu, Xiaoyong Xu*.Design, Synthesis and Particular Biological Behaviors of Chain-opening Nitromethylene Neonicotinoids with cis-Configuration. J. Agric. Food Chem.,2012, 60(1), 322-330.

36  anli Wang, Tian Liu, Qing Yang, Zhong Li, Xuhong Qian*. A Modeling Study for Structure Features of β-N-acetyl-D-hexosaminidase from Ostrinia furnacalis and its Novel Inhibitor Allosamidin: Species Selectivity and Multi-Target Characteristics.Y. Chem. Biol. Drug. Des.  2012, 79(4), 572–582.

37  Xusheng Shao*, Xinglong Huang, Qian Shi, Zhong Li, Liming Tao, Gonghua Song*. Synthesis and Insecticidal Activities of Chlorothiazolyl Analogues of Nitromethylene Neonicotinoids with Tetrahydropyridine Fixed cis-Configuration. J. Heterocyclic Chem.,  2012, 49(5), 1136-1142.



1  Huang JinZhaoZhenjiangXu Yuang, Li Honglin. Identification of Inhibitors against p90 Ribosomal S6 Kinase 2 (RSK2) through Structure-Based Virtual Screening with the Inhibitor-Constrained Refined Homology Model. Journal of Chemical Information And Modeling. 2011, 51(11):2939-2947. 

2  ZhaoZhenjiang, Huang Jin, Li Honglin. SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 2. Prospective Case Study in the Discovery of Diverse p90 Ribosomal S6 Protein Kinase 2 Inhibitors To Suppress Cell Migration. J.Med.Chem.,  2011,54(10):3564-3574.

3  Huang JinLi Honglin .Fast and effective identification of the bioactive compounds and their targets from medicinal plants via computational chemical biology approach. Med. chem. comm., 2011;2(6):471-477.

4  LiHonglinHuang Jin. HL005-A new selective PPAR gamma antagonist specifically inhibits the proliferation of MCF-7. J Steroid Biochem Mol Biol., 2011;124(3-5):112-120.

5  SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 1. Method and Assessment of Virtual Screening  Li Honglin  JOURNAL OF CHEMICAL INFORMATION AND MODELING  2011;51(9):2372-2385  3.822 

6  Li Honglin. Accelerating All-Atom Normal Mode Analysis with Graphics Processing Unit    Journal of Chemical Theory And Computation,2011;7(6):1595-1603.

7  Li Honglin. Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica.Chem. Commun., 2011, 47, 1222-1224. 

8  Li Honglin.Establishment of platform for screening insulin-like growth factor-1 receptor inhibitors and evaluation of novel inhibitors. Acta Pharmacol Sin., 2011, 32(7), 930-938. 

9 Feng Huangdi;Ermolat'e v, Denis S.;Song, Gonghua;Van der Eycken, Erik V. Microwave-Assisted Decarboxylative Three-Component Coupling of a 2-Oxoacetic Acid, an Amine, and an Alkyne. Journal Of Organic Chemistry, 2011,76(18),7608-7613.

10  Zeng Tieqiang; Yang Luo; Hudson Reuben;Song Gonghua;Moores, Audrey R.;Li, Chao-Jun. Fe(3)O(4) Nanoparticle-Supported Copper(I) Pybox Catalyst: Magnetically Recoverable Catalyst for Enantioselective Direct-Addition of Terminal Alkynes to Imines.Organic Letters,    2011,13(3),442-445.

11  Kang Li-Qin; Cai Yue-Qin; Peng Yan-Qing; Ying, Xi-Li;Song Gonghua.Silica-supported sulfonic acid-functionalized ionic liquid coated with [bmim][PF(6)] as a scavenger for the synthesis of amides.Molecular Diversity, 2011,15(1),109-113.

12  Song Cao,JingJing Wu, JianHang Cheng, Jian Zhang, Li Shen, XuHong Qian. Non-catalytic conversion of C-F bonds of gem-difluoromethylene derivatives to C-H bonds with lithium aluminum hydride under room temperature.Tetrahedron, 2011,67, 285-288.

13  Song Cao,Mingxi Wu, Jinlong Yu, Wenwen Zhao, Jingjing Wu.One-pot synthesis of difluoromethyl-containing dihydropyrimidinones catalyzed by Yb(PFO)3 under solvent and dehydrating agent free conditions. J Fluorine Chem, 2011,132, 155-159.

14 Song Cao,Jian Zhang, Jingjing Wu, Li Shen, Guanyi Jin. Novel synthesis of difluoromethyl-containing 1,4-disubstituted 1,2,3-triazoles via a click-multicomponent reaction and desulfanylation strategy. Adv Synth Catal , 2011,353, 580-584.

15 Song Cao,Jianhang Cheng, Jingjing Wu.ZnCl2-catalyzed hydrodefluorination of gem- difluoromethylene derivatives with lithium aluminum hydride.Tetrahedron Letters, 2011,52, 3481-3484.

16 Song Cao,Jingjing Wu.Nickel-Catalyzed Hydrodefluorination of Fluoroarenes and Trifluorotoluenes with Superhydride (Lithium Triethylborohydride).Chem.Cat.Chem,  2011,3(10), 1582-1586.

17  Ingo Ott*, Yufang Xu, Xuhong Qian*. Fluorescence properties and antiproliferative effects of mono-, bis-, and tris-thiophenylnaphthalimides: Results of a comparative pilot study.    Journal of Photochemistry and Photobiology B:Biology, 2011, 105(1): 75-80.

18 Xin Liang, Ke Xu, Yufang Xu, Jianwen Liu*, Xuhong Qian*. B1-induced caspase- independent apoptosis in MCF-7 cells is mediated by down-regulation of Bcl-2 via p53 binding to P2 promoter TATA box. Toxicology and Applied Pharmacology,2011, 256(1): 52-61.

19  Ke Xu, Xin Liang, Fang Wang, Lijuan Xie, Yufang Xu, Jianwen Liu*, Xuhong Qian*.  Induction of G(2)/M phase arrest and apoptosis by potent antitumor APCA in human cervix carcinoma cells. Anticancer Drugs, 2011, 22(9): 875-885.

20  Xin Liang, Aibin Wu, Yufang Xu, Ke Xu, Jianwen Liu*, Xuhong Qian* .B1, a novel naphthalimide-based DNA intercalator, induces cell cycle arrest and apoptosis in HeLa cells via p53 activation. Investigational New Drugs, 2011, 29(4): 646-658.

21  Junhong Qian, Yufang Xu, Shitong Zhang, Xuhong Qian*. A Supramolecular Off-On Fluorescent Switch and IMPLICATION Logic Gate for Detection of Cationic Surfactant.    Journal of Fluorescence, 2011, 21(3): 1015-1020.

22  Aibin Wu*, Ping Mei, Yufang Xu, Xuhong Qian. Novel Naphthalimide-Benzoic Acid Conjugates as Potential Apoptosis-Inducing Agents: Design, Synthesis, and Biological Activity. Chemical Biology & Drug Design, 2011, 78(6): 941-947. 

23  Lijuan Xie, Jingnan Cui, Xuhong Qian*, Yufang Xu, Jianwen Liu, Ruian Xu. 5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior. Bioorganic & Medicinal Chemistry, 2011, 19(2): 961-967.

24  Hong Yin, Weiping Zhu, Yufang Xu*, Min Dai, Xuhong Qian*.Novel aliphatic N-oxide of naphthalimides as fluorescent markers for hypoxic cells in solid tumor. European Journal of Medicinal Chemistry, 2011, 46, 3030-3037. 

25  Shenyi Zhang, Chunmei Yang, Weiqiang Lu, Jin Huang, Weiping Zhu, Honglin Li, Yufang Xu* and Xuhong Qian*.A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging. Chemical Communication, 2011, 47, 8301-8303.

26  Tanyu Cheng, Tao Wang, Weiping Zhu, Xinlei Chen, Youjun Yang, Yufang Xu,* and Xuhong Qian*. Red-Emission Fluorescent Probe Sensing Cadmium and Pyrophosphate Selectively in Aqueous Solution. Organic Letters, 2011, 13, 3656-3659. 

27  Zhuo Chen, Xin Wang, Weiping Zhu, Xianwen Cao, Linjiang Tong, Honglin Li, Hua Xie, Yufang Xu*, Shaoying Tan, Dong Kuang, Jian Ding, and Xuhong Qian*. Acenaphtho[1,2-b] pyrrole-Based Selective Fibroblast Growth Factor Receptors 1 (FGFR1) Inhibitors: Design, Synthesis, and Biological Activity.Journal of Medicinal Chemistry, 2011, 54(11), 3732-3745.

28  Tanyu Cheng, Tao Wang, Weiping Zhu, Yangyang Yang, Bubing Zeng, Yufang Xu* and Xuhong Qian*. Modulating the selectivity of Near Infrared Fluorescent Probes Toward Various Metal Ions by Judicious Choice of Aqueous Buffer Solutions. Chemical Communication,  2011, 47, 3915-3917.

29  Lei Cui, Ye Zhong, Weiping Zhu, Yufang Xu,* Qingshan Du, Xin Wang, Xuhong Qian,* and Yi Xiao.A New Prodrug-Derived Ratiometric Fluorescent Probe for Hypoxia: High Selectivity of Nitroreductase and Imaging in Tumor Cell. Organic Letters, 2011, 13, 928-931.

30  Yangyang Yang, Tanyu Cheng, Weiping Zhu, Yufang Xu*, Xuhong Qian*.Highly Selective and Sensitive Near-infrared Fluorescent Sensors for Cadmium in Aqueous Solution.    Organic Letters, 2011, 13, 264-267.

31  Chusen Huang, Qin Yin, Weiping Zhu*, Yi Yang*, Yufang Xu*, Xin Wang, and Xuhong Qian. Highly selective fluorescent probe for vicinal dithiol-containing proteins and in-situ imaging in living cells. Angewandte Chemie International Edition, 2011, 50, 7551-7556. 

32  Chunsheng He, Xuhong Qian*, Yufang Xu, Chunmei Yang, Liyan Yin, Weiping Zhu*.A Ratiometric Fluorescent Probe for Oxalate Based on Alkyne-conjugated Carboxamido- quinolines in Aqueous Solution and Imaging in Living Cells. Dalton Transactions,2011, 40, 1034-1037.

33  Lin Xu, Yufang Xu, Weiping Zhu, Bubing Zeng, Chunmei Yang, Bin Wu and Xuhong Qian*.Versatile trifunctional chemosensor of rhodamine derivative for Zn2+, Cu2+ and His/Cys in aqueous solution and living cells. Organic and Biomolecular Chemistry, 2011, 9, 8284-8287.

34  Li, X. L.; Lin, Y. J.; Wang, Q. Q.; Yuan, Y. K.; Zhang, H.; Qian, X. H.The novel anti-tumor agents of 4-triazol-1,8-naphthalimides: Synthesis, cytotoxicity, DNA intercalation and photocleavage. European Journal of Medicinal Chemistry, 2011, 46 (4), 1274-1279.

35  Li, X. L.; Lin, Y. J.; Yuan, Y. K.; Liu, K.; Qian, X. H.Novel efficient anticancer agents and DNA-intercalators of 1,2,3-triazol-1,8-naphthalimides: design, synthesis, and biological activity.Tetrahedron , 2011, 67 (12), 2299-2304.

36  Xiao, Y.; Zhang, D. K.; Qian, X. H.; Costela, A.; Garcia-Moreno, I.; Martin, V.; Perez-Ojeda, M. E.; Banuelos, J.; Gartzia, L.; Arbeloa, I. L.Unprecedented laser action from energy transfer in multichromophoric BODIPY cassettes. Chemical Communications, 2011, 47 (41), 11513-11515.

37  Xie, L. J.; Cui, J. N.; Qian, X. H.; Xu, Y. F.; Liu, J. W.; Xu, R. A.5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior. Bioorganic & Medicinal Chemistry,  2011, 19 (2), 961-967. 

38  Yu, H. B.; Xiao, Y.; Guo, H. Y.; Qian, X. H.Convenient and Efficient FRET Platform Featuring a Rigid Biphenyl Spacer between Rhodamine and BODIPY: Transformation of 'Turn-On' Sensors into Ratiometric Ones with Dual Emission. Chemistry-a European Journal,  2011, 17 (11), 3179-3191.

39  Kishore Baathulaa, Yufang Xu, Xuhong Qian*. Short and Scalable Synthesis of an Anhydride Precursor of the Environment-sensitive Fluorophore 6-DMN. Nature Protocols  2011, 6,1990-1997. 

40  Huang, XGLiu, J.; Ren, JM.; Wang, T.; Chen, WD.; Zeng, BB. A facile and practical one-pot synthesis of multisubstituted 2-aminothiophenes via imidazole-catalyzed Gewald reaction.Tetrahedron, 2011, 6202.

41  Hua, SK.; Wang, J. ; Chen, XB .; Xu, ZY.; Zeng, BB. Scalable synthesis of methyl ent-isocopalate and its derivatives. Tetrahedron, 2011, 1142.

42  Xusheng Shao, Philip W. Lee, Xiaoyong Xu, Zewen Liu, Zhong Li*, Xuhong Qian. cis-Configuration: A New Tactic/Rationale for Neonicotinoid Molecular Design. Journal of Agricultural and Food Chemistry, 2011,59, 2943–2949.

43  Xusheng Shao, Hanyan Liu, Haibo Bao, Xiaoyong Xu, Zewen Liu*, Zhong Li*.The Mode of Action of a Nitroconjugated Neonicotinoid and the Effects of Target Site Mutation Y151S on its Potency. Insect Biochemistry and Molecular Biology, 2011, 41, 440–445. 

44  Zhenjun Ye, Shuang Xia, Xusheng Shao, Jiagao Cheng, Xiaoyong Xu, Zhiping Xu, Zhong Li*, Xuhong Qian*. Design Synthesis, Crystal Structure Analysis, and Insecticidal Evaluation of Phenylazoneonicotinoids. Journal of Agricultural and Food Chemistry,2011, 59, 10651–10623.

45  Xusheng Shao, Zhenjun Ye, Haibo Bao, Zewen Liu, Xiaoyong Xu, Zhong Li*, Xuhong Qian*. Advanced research on cis-neonicotinoids. Chimia, 2011, 65, 957–960. 

46  Lijuan Sun, Jianwen Liu, Ping Liu, Youjun Yu, Lei Ma, Lihong Hu. Immunosuppression effect of Withangulatin A from Physalis angulata via heme oxygenase 1-dependent pathways.    Process Biochem. , 2011,46 482–488.

47  Zijing Jiang, Tiantian Jin, Feng Gao, Jianwen Liu, Jianjiang Zhong , Heng Zhao. Effects of Ganoderic acid Me on inhibiting multidrug resistance and inducing apoptosis in multidrug resistant colon cancer cells. Process Biochem. , 2011,46 1307–1314.



1  Qian Xuhong. Pattern-based sensing of short oligodeoxynucleotides with palladium–dye complexes .Chemical Communications,2010, 46, 5515–5517. 

2  Qian Xuhong. A fluorescent sensor for pyrophosphate based on a Pd(II) complex. Dalton Transactions, 2010, 39 (30): 7114-7118.

3  Qian Xuhong .A design concept of planar conjugated ladder oligomers of perylene bisimides and efficient synthetic strategy via regioselective photocyclization. Chemical Communications,2010, 46 (16): 2772-2774.

4  Qian Xuhong. Core-Perfluoroalkylated Perylene Diimides and Naphthalene Diimides: Versatile Synthesis, Solubility,Electrochemistry, and Optical Properties    Journal of Organic Chemistry,2010, 75 (9): 3007-3016.

5  Xu Yufang, Liu Jianwen, Qian Xuhong .B1, a Novel Amonafide Analogue, Overcomes the Resistance Conferred by Bcl-2 in Human Premyelocytic Leukemia HL60 Cells.    Molecular Cancer Research, 2010, 8(12), 1619-1632. 

6  Xu Yufang, Qian Xuhong. Unusual large stokes shift and Solvatochromic fluorophore: Synthesis, spectra, solvent effect of 6-substituted 2,3-naphthalimide. Journal of Photochemistry and Photobiology A: Chemistry,2010, 216, 24-34.

7  Zhu Weiping, Xu Yufang, Qian Xuhong .Ratiometric and Reusable Fluorescent Nanoparticles for Zn2+ and H2PO4- Detection in Aqueous Solution and Living Cell.Journal of Materials Chemistry, 2010, 20, 10755-10764.

8  Xu Yufang, Qian Xuhong. Novel naphthalimide–indomethacin hybrids as potential antitumor agents: effects of linkers on hypoxic/oxic cytotoxicity and apoptosis-inducing activity.    Monatsh Chem, 2010, 141, 893–899.

9  Zhu Weiping, Xu Yufang, Qian Xuhong .Selective and Sensitive Detection and Quantification of Arylamine N-Acetyltransferase 2 by a Ratiometric Fluorescence Probe.Chemical Communications, 2010, 46, 7121 – 7123.

10  Qian Xuhong, Xu Yufang, Zhu Weiping .“Alive” Dye as Fluorescent Sensor: Fluorophore, Mechanism, Receptor and Images in Living Cell . Chemical Communications, 2010, 46, 6418 – 6436.

11  Liu Jianwen, Xu Yufang, Zhu Weiping, Qian Xuhong. A New Class of Naphthalimide-based Antitumor Agents that Inhibit Topoisomerase II (Topo II) and Induce Lysosomal Membrane Permeabilization (LMP) and Apoptosis.Journal of Medicinal Chemistry,2010, 53, 2589–2600 

12  Zhu Weiping, Xu Yufang, Qian Xuhong. A Thioether-Rich Crown-Based Highly Selective Fluorescent Sensor for Hg2+ and Ag+ in Aqueous Solution. Dalton Transactions, 2010, 39, 1316-1320.

13  Cao SongQian Xuhong .K2CO3-assisted one-pot sequential synthesis of 2-trifluoromethyl-6-difluoromethylpyridine-3,5-dicarboxylates under solvent-free conditions.  Tetrahedron Letters, 2010, 51, 4866-4869.

14  Cao SongQian Xuhong.  A mild and efficient synthesis of monofluorinated-lactam pseudopeptides via a novel dehydrofluorination of Ugi products. Mol Divers,2010, 14, 501-506.

15  Cao SongQian Xuhong. An efficient three-component domino synthesis of difluoromethyl-containing 1,4-dihydropyridines under solvent and catalyst free conditions.  Science China Chemistry,2010, 53(7), 1509-1513.

16  Cao Song. A General Strategy for Construction of Difluoromethyl Compound Library and its Application in Synthesis of Pseudopeptides bearing. Org. Biomol. Chem., 2010, 8,  2386-2391.

17  Cao Song. Synthesis and Insecticidal Activity of Heptafluoroisopropyl-Containing Benzoylphenylurea Structures.J. Agric. Food Chem., 2010, 58(5), 2736-2740. 

18  Jianwen Liu.Investigation of the immunosuppressive activity of Physalin H on T lymphocytes.International Immunopharmacology,2010,10,290-297.

19  JianwenLiuMinbo Lan.Nano-SiO2 induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cell line.Toxicology in Vitro,2010,24,751-758.

20  JianwenLiuXuhong Qian. B1, a novel naphthalimide-based DNA intercalator, induces cell cycle arrest and apoptosis in HeLa cells via p53 activation.Invest New Drugs, 2010.

21  Jianwen Liu,Jiyu Li. Anti-Inflammatory Function of Withangulatin A by Targeted Inhibiting COX-2 Expression. Journal of Cellular Biochemistry, 2010,109,532-541.

22  Zhong Li .One-pot synthesis of polyfunctionalized 4H-pyran derivatives bearing fluorochloro pyridyl moi ety.Tetrahedron Lett., 2010,51,4991-4994.

23  Zhong Li. Design, Multicomponent Synthesis, and Bioactivities of Novel Neonicotinoid Analogues with 1,4-Dihydropyridine Scaffold.Journal of Agricultural and Food Chemistry 2010,58,2741-2745.

24  Zhong Li .Designing Tetrahydroimidazo[1,2-a]pyridine Derivatives via Catalyst-free Aza-Diels-Alder Reaction (ADAR) and Their Insecticidal Evaluation. Journal of Agricultural and Food Chemistry, 2010,58,6296-6299.

25  Xiaoyong Xu,Zhong Li. Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid: Design, Synthesis, Crystal Structure and Insecticidal Activities  Journal of Agricultural and Food Chemistry, 2010,58,2696-2702 .

26  Xiaoyong Xu,Zhong Li. Synthesis, Crystal Structure and Insecticidal Activities of Highly Congested Hexahydroimidazo[1,2-α]pyridine Derivatives as Novel Neonicotinoids: Effect of Conformation on Activities.Journal of Agricultural and Food Chemistry, 2010,58,2690-2695.

27  Xiaoyong Xu,Zewen Liu, Zhong Li. Pharmacological of cis-Nitromethylene neonicotinoids: overlapping one binding site of imidacloprid in the brown planthopper, Nilaparvata lugens. Insect Molecular Biology, 2010,19,1-8.

28  ZhongLi,Gonghua Song . Design and Synthesis of Novel Insecticides Based on Serotonergic Ligand PAPP. Journal of Agricultural and Food Chemistry, 2010,58,2624-2629.

29  Zhong Li ,N ovel Dimer Based Descriptors with Solvational Computation for QSAR Study of Oxadiazoylbenzoyl-ureas as Novel Insect-growth Regulator. Journal of Computational Chemistry , 2010,31,586-591.

30  Xiaoyong Xu .Photodegradation of Novel Nitromethylene Neonicotinoids with Tetrahydropyridine-Fixed cis Configuration in Aqueous Solution.Journal of Agricultural and Food Chemistry, 2010,58,2746-2754.

31  Xiaoyong Xu,Bubing Zeng .An Efficient One-Pot Synthesis of Substituted 2-Aminothiophenes via. Synlett 2010,9,1351-1354.

32  徐晓勇.1,4-二氢吡啶环的新烟碱类化合物的合成及杀虫活性.农药学学报,2010,


33  程家高.μ/δ 阿片受体相互调节作用及药物发现与设计策略.中国药理学通报, 2010, 26, 4-8.

34  Synthesis, biological assay in vitro and molecular  Gonghua Song  European Journal of  2010, 45, 4953-4962.

35  Gonghua Song, Chao-Jun Li .Magnetically Recoverable Iron Nanoparticle Catalyzed Cross-Dehydrogenative Coupling (CDC) between Two Csp3–H Bonds Using Molecular Oxygen. SYNLETT, 2010, 13, 2002–2008.

36  Gonghua Song, Chao-Jun Li. Fe3O4 nanoparticles: a robust and magnetically recoverable catalyst for three-component coupling of aldehyde, alkyne and amine. Green Chem.,  2010, 12, 570–573.

37  Guiyun Li, Yanqing Peng. Two birds with one stone: redox co-production of 2-arylbenzothiazoles and hydroquinone. Monatsh. Chem., 2010, 141, 45–48.

38  Hengyao Hu, Hao Yanqing Peng. Unique Role of Ionic Liquid in Microwave-assisted Synthesis of Monodisperse Magnetite Nanoparticles.Chem. Commun., 2010, 46, 3866–3868. 

39  Yanqing Peng. Efficient Methyl Esterification Using Methoxyl Silica Gel as a Novel Dehydrating Reagent .J. Chin. Chem. Soc., 2010, 57, 305-308. 

40  Honglin Li. PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach. Nucleic Acids Research, 2010, 38,W609–W614.

41  Honglin Li .Discovery and SAR of Thiazolidine-2,4-dione Analogues as Insulin-like Growth Factor-1 Receptor (IGF-1R) Inhibitors via Hierarchical Virtual Screening.Journal of Medicinal Chemistry, 2010, 53 (6),2661–2665.

42  Honglin Li. Bioactive Conformational Generation of Small Molecules: A Comparative Analysis between Force-Field and Multiple Empirical Criteria Based Methods.BMC Bioinformatics ,2010, 11,545.

43  Qingchun Huang. Comparable Susceptibility of Human 293 Cells and Insect Tn-5B1-4 Cells to Photoactivated α-Terthienyl. J. Agric. Food Chem., 2010, 58(5), 2637-2642.

44  Qinchun Huang. Recent progress of highly efficient in vivo biological screening for novel agrochemicals in China.Pest Manag. Sci., 2010, 66, 107-112.

45  Qingchun Huang. Differential synergism of fipronil by piperonyl butoxide in the susceptible and resistant Chilo suppressalis .J. Insect Sci., 2010, 10:162.

46  Qingchun Huang. Novel 2’-hydroxylfurylchalcones: Synthesis and biological activity  Carbohydrate Research, 2010, 345, 1872-1876 . 

47  Qing Yang. Structural Determinants of an Insect_-N-Acetyl-D-hexosaminidase Specialized as a Chitinolytic Enzyme. Journal Of Biological Chemistry, 2010,M110.184796.

48  Yi Xiao. Switching off FRET by analyte-induced decomposition of squaraine energy acceptor: A co ncept to transform ‘turn off’ chemodosimeter into ratiometric sensors    Physical Chemistry Chemical Physics ,2010, 12, 7386–7391.

49  Xiaoyong Xu, Xuhong Qian. Solvent effects for fluorescence and absorption tetra(fluoroalkyl) metallophthalocyanines: Fluorocarbon solvent cage. Journal of Photochemistry and Photobiology A: Chemistry, 2010, 214, 86–91.


1. Aibin Wu, Yufang Xu, Xuhong Qian*, Jin Wang, Jianwen LiuNovel naphthalimide derivatives as potential apoptosis–inducing agents: Design, synthesis and biological evaluationEJMC, 2009, in press

2. Xu Yufang, Lu Feng, Xu ZhaoChao, Cheng Tanyu & Qian Xuhong, Highly sensitive and selective ratiometric fluorescent copper sensors: Different binding affinities modulated by three separate side chains of naphthalimide, Science in China Series B: Chemistry 2009,52,771-779

3. Jin Wang, Aibin Wu, Yufang Xu, Jianwen Liu *, Xuhong Qian * M2-A induces apoptosis and G2–M arrest via inhibiting PI3 K/Akt3 pathway in HL60 cells Cancer Letters in press, 2009,

4. Lijuan Xie,Yufang Xu, Fang Wang, JianwenLiu,Xuhong Qian*, Jingnan Cui*, Synthesis of new amonafide analogues via coupling reaction and their cytotoxic evaluation and DNA-binding studies, Bioorg. Med. Chem., 2009, 17, 804-810

5. Aibin Wu, Yufang Xu, Xuhong Qian*, Novel naphthalimide–amino acid conjugates with flexible leucine moiety as side chain: Design, synthesis and potential antitumor activity, Bioorg. Med. Chem., 2009, 17, 592-599

6. Junhai Huang, Yufang Xu, Xuhong Qian*, A Rhodamine-based Sensor for Real-time Determination of Hg2+ with High Selectivity and Sensitivity in Aqueous Solution: The Integration of Cyclic Conversion and NS2-contained Receptor, J. Org. Chem., 2009, 74, 2167-2170

7. Junhai Huang, Yufang Xu, Xuhong Qian*, A Red-shift Colorimetric and Fluorescent Sensor for Cu2+ in Aqueous Solution: Unsymmetrical 4,5-Diaminonaphthalimide with N-H Deprotonation Induced by Metal Ion, Org. Biomol. Chem., 2009,7,1299-1303

8. Ingo Ott, Xuhong Qian, Yufang Xu, N. N. Univ. Leiden, Dominik Kubat, Joanna Will, Patrick Jesse, Aram Prokop, Christoph Bagowski, William S. Sheldrick, A luminescent gold (I) phosphine complex containing a naphthalimide ligand as TrxR inhibiting antiproliferative agent and angiogenesis inhibitor. J. Med. Chem. 2009, 52,763-770

9. Junhai Huang, Yufang Xu, Xuhong Qian*, A Colorimetric Sensor for Cu2+ in Aqueous Solution Based on The Metal Ion-induced Deprotonation: Deprotonation/Protonation Mediated by Cu2+-ligand Interactions Dalton Transactions2009, 1761–1766.

10. Junhong Qian, Xuhong Qian, Yufang Xu, Shenyi Zhang ,Selective and Sensitive Chromo- and Fluorogenic Dual Detection of Anionic Surfactants in Water Based on a Pair of On-Off-On Fluorescent Sensors, Chemistry - A European Journal, 2009,15(2), 319-323

11. Liping Duan, Yufang Xu, Xuhong Qian,Yexiang Zhang, Yang Liu, Novel naphthalimide derivatives with near-infrared emission: Synthesis via photochemical cycloaromatization, fluorescence in solvents and living cell , Tetrahedron Lett.,2009, 50, 22–25

12.  Feng Fan, Jiagao Cheng, Zhong Li*, Xiaoyong Xu, Xuhong Qian*. “Novel dimer based descriptors with solvational computation for QSAR study of oxadiazoylbenzoyl-ureas as novel isect-growth regulators”. Journal of Computational Chemistry. 2009, published online, DOI: 10.1002/jcc.2135

13. Feng Fan, Zhiqi You, Zhong Li*, Jiagao Cheng, Yun Tang, Zhenhua Tang. “A Butterfly Effect: Highly Insecticidal Resistance Caused by Only a Conservative Residue Mutated of Drosophila Melanogaster Acetylcholinesterase”. Journal of Molecular Modeling, 2009, 15, 1229-1236

14.  Xusheng Shao, Zhong Li*, Xuhong Qian, Xiaoyong Xu*. “Design, Synthesis, and Insecticidal Activities of Novel Analogues of Neonicotinoids: Replacement of Nitromethylene with Nitroconjugated System”. J. Agric. Food Chem. 2009, 57, 951–957

15.  Tingting Cao, Yipei Ma, Xiuhua Yan, Jiagao Cheng*, Youhua Luo,  Liming He,  Weiliang Zhu*. “Is Free Cyclooctatetraene Dianion an Aromatic System? A Quantum Chemistry Study”, Chinese Journal of Chemistry 2009, 27, 1914-1918

16. Feng Fan, Jin Zhu, Shuaishuai Ni, Jiagao Cheng*, Yun Tang, Congmin Kang, Jian Li*, Hualiang Jiang. “Pharmacophore Refinement and 3D-QSAR Studies of Inhibitors of Cyclophilin A Containing Amide Linker” QSAR & Combinatorial Science, 2009, 28, 183-193


1. Tanyu Cheng, Yufang Xu,* Shenyi Zhang, Weiping Zhu, Xuhong Qian,* Liping Duan A highly sensitive and selective OFF-ON fluorescent sensor for cadmium in aqueous solution and living cell,  J. Am. Chem. Soc., 2008, 130 (48). 16160–16161

2. Liping Duan, Yufang Xu, Xuhong Qian, Highly Sensitive and Selective Pd2+ Sensor of Naphthalimide Derivative Based on Complexation with Alkynes and Thio-heterocycleChem. Commun. 2008, 6339-6341

3. Liping Duan,Yufang Xu, Xuhong Qian, Fang Wang, Jianwen Liu, Tanyu Cheng, Highly Selective Fluorescent Chemosensor with Red Shift for Cysteine in Buffer Solution and Its Bioimage: Symmetrical Naphthalimide Aldehyde, Tetrahedron Lett., 2008, 49,6624-6627

4. Junhong Qian, Yufang Xu, Xuhong Qian, Shenyi Zhang. Molecular Logic Operations Based on Surfactant Nano-aggregates: Premicelle, Micelle and Its Formation Induced by Inorganic Salt. ChemPhyChem, 2008, 9, 1891-1898

5. Junhong Qian, Yufang Xu, Xuhong Qian, Jiaobing Wang, Shenyi Zhang. Effects of Anionic Surfactant SDS on the Photophysical Properties of Two Fluorescent Molecular Sensors. J. Photochem. Photobiol. A , Chemistry, 2008,200,402–409

6. Ingo Ott, Yufang Xu, Jianwen Liu, Malte Kokoschka, Melanie Harlos, William S. Sheldrick, Xuhong Qian ,Sulfur Substitued Naphthalimides as Photoactivatable Anticancer Agents: DNA Interaction, Fluorescence Imaging and Phototoxic Effects in Cultured Tumor Cells, Bioorg. Med. Chem., 2008, 16, 7107-7116

7. Junhong Qian, Xuhong Qian, Yufang Xu, Shenyi Zhang. Multiple Molecular Logic Functions and Molecular Calculation Facilitated by Surfactant with its Versatility. Chem. Commun. 2008, 4141–4143

8. Meiyan Fu, Yi Xiao, Xuhong Qian, Defeng Zhao, Yufang Xu, A design concept of long- wavelength fluorescent analogs of rhodamine dyes: replacement of oxygen with silicon atom, Chem. Commun., 2008, 1780–1782

9. Weiping Zhu, Zhenjiang Zhao, Yufang Xu,* Derivatives of Benzothiadiazole-7- Carboxylates: Synthesis and Biological ActivityMonatshefte fur Chemie2008,391067-1071

10. Min Dai Weiping Zhu Yufang Xu* Xuhong Qian* Yan Liu Yi Xiao Yin YouVersatile Nitro-Fluorophore as Highly-effective Sensor for Hypoxic Tumor Cells: Design, Imaging and EvaluationJournal of Fluorescence, 2008,18, 591-597,

11. Weiping Zhu, Min Dai, Yufang Xu*, Xuhong Qian* , Novel Nitroheterocyclic Hypoxic Markers for Solid Tumor: Synthesis and Biological Evaluation, Bioorganic and medicinal chemistry, 2008,16,3255-3260,

12. Chuanxiang Liu, Xuhong Qian,* Guangqiang Sun, Liwei Zhao and Zhong Li*, “Chromogenic and fluorescent chemodosimeter for fluoride ion based on novel anion-catalyzed intramolecular hydrogen transfer”, New J. of Chem. 2008, 32, 472-476

13. Gangyue Li, Xuhong Qian*, Shenggang Yan, Jingnan Cui, Rong Zhang, Yi Xiao, “Synthesis, herbicidal activity, and structure-bioactivity relationship of pyridyl-containing 2-phenyliminothiazolidines”, Monatsh. Chem.   2008, 139,  169-178

14. Nianjin Liu, Song Cao*, Jingjing Wu, Jinlong Yu, Li Shen, Xin Feng, Xuhong Qian*, “Solvent-Free Ugi Four-Component Condensation: Application to Synthesis of Philanthotoxins-12 Analogues”, Tetrahedron 2008, 64, 3966-3974

15. Song Cao*, Jingjing Wu, Lina Li, Longjie Zhu, Jian Zhang, Jinlong Yu, Xuhong Qian, “One-Pot Three Component Synthesis of Heteroaryled arylacetates via VNSAr-SN Reaction using N-Methylpyrrolidone as General Solvent”, Org. Biomol. Chem. 2008, 6, 1293-1297

16. Li Shen, Song Cao*, Nianjin Liu, Jingjing Wu, Xin Feng, Xuhong Qian*, “Ytterbium (III) Perfluorooctanoate-catalyzed One-pot Three-component Synthesis of Fully Substituted Pyrazoles under Solvent-free Conditions”, Synlett. 2008, 1341-1344

17. S. Cao*, L. J. Zhu, Chuanmeng Zhao, Xiuhong Tang, Huajun Sun, Xin Feng, and Xuhong Qian, Synthesis of Thiohydantoins under One-Pot Three-Component Solvent-Free Conditions, Monatsh. Chem. 2008, published online

18. Chuanxiang Liu, Xuhong Qian *, Jiaobing Wang, Zhong Li *, “Anion recognition by a novel Fipronil-based receptor: efficient deprotonation or stable intermolecular hydrogen bonding”, Tetrahedron Lett. 2008, 49, 1087-1090

19. Xuhong Qian, et al., Isomeric Boron-Fluorine Complexes with Donor-Acceptor Architecture: Strong Solid/Liquid Fluorescence and Large Stokes Shift., Org. Lett., 2008, 10, 633- 636

20. Xuhong Qian, et al., Novel Fluorescent Fluorine-Boron Complexes: Synthesis, Crystal Structure, Photoluminescence, and Electrochemistry Properties., J. Org. Chem., 2008, 73, 1571-1574

21. Qingchun Huang, et al., Effect of oxadiazolyl 3(2H)-pyridazinone on the larval growth and digestive physiology of the armyworm, Pseudaletia separata, J. Insect. Science, 2008, 8, 19

22. Qingchun Huang, et al., Effect of dietary benzoxadiazole on larval development, cuticle enzyme and antioxidant defense system in housefly (Musca domestica L.), Pestic. Biochem. Phys., 2008, 90, 119-125

23. Yanqing Peng, et al., Chloroferrate(III) ionic liquid: Efficient and recyclable catalyst for solvent-free synthesis of 3,4-dihydropyrimidin-2(1H)-ones, Catal. Lett., 2008, 122, 310-313

24. Weiping Zhu, Yufang Xu, Xuhong Qian, et al., Versatile nitro-fluorophore as highly effective sensor for hypoxic tumor cells: Design, imaging and evaluation, J. Fluorescence 2008, 6, 591-597

25. Weiping Zhu, Yufang Xu, Xuhong Qian, et al., Novel nitroheterocyclic hypoxic markers for solid tumor: Synthesis and biological evaluation, Bioorg. Med. Chem. 2008, 16, 3255-3260

26. Xuhong Qian, et al., Ratiometric and water-soluble fluorescent zinc sensor of carboxamidoquinoline with an alkoxyethylamino chain as receptor, Org. Lett. 2008, 10, 473-476

27. Xuhoang Qian, et al., Highly efficient energy transfer in the light harvesting system composed of three kinds of boron-dipyrromethene derivatives, Org. Lett. 2008, 10, 29-32

28.  Lingyan He§, Jiagao Cheng§, Tao Wang, Caimei Li, Zhen Gong, Hong Liu, Bu-Bing Zeng, Hualiang Jiang, Weiliang Zhu, "Cation-π complexes formed between cyclooctantetraene and alkaline earth metals: predicted and recorded NMR features", Chem. Phys. Lett. 2008, 462, 45-58. (§并列第一作者)

29.  Jiagao Cheng, WeiLiang Zhu, YanLi Wang, XiuHua Yan, Zhong Li, Yun Tang, HuaLiang Jiang,"The Open-Close Mechanism of M2 Channel Protein in Influenza A Virus: A Computational Study on the Hydrogen Bonds and Cation-pi interactions among His37 and Trp41", Sci. China Ser.B-Chem, 2008, 51, 768-775.

30.  Jiagao Cheng, XiaoMin Luo, XiuHua Yan, Zhong Li, Yun Tang, HuaLiang JiangWeiLiang Zhu,"Research Progress in Cation-pi interactions", Sci. China Ser.B-Chem, 2008, 51, 709-717.



1.  Jiaobing Wang, Xuhong Qian, Junhong Qian*, Yufang Xu, “Micelle-Induced Versatile Performance of Amphiphilic Intramolecular Charge-Transfer Fluorescent Molecular Sensors”. Chem. Eur. J. 2007, 13, 7543-7552

2.  Zhongzhen Tian, Zhaoxing Jiang, Zhong Li,* Gonghua Song,* and Qingchun Huang, “Syntheses and Biological Activities of octahydro-1H-cyclopenta[d] pyrimidine derivatives”. J. Agric. Food Chem. 2007, 55, 143-147

3.  Zhongzhen Tian, Xusheng Shao, Zhong Li,* Xuhong Qian,* “Synthesis, Insecticidal Activity, and QSAR of Novel Nitromethylene Neonicotinoids with Tetrahydropyridine Fixed cis Configuration and Exo-Ring Ether Modification”, J. Agric. Food Chem. 2007, 55,  2288-2292

4. Feng Fan, Zhong Li*, Xiaoyong Xu, Xuhong Qian*, “Quantitative Aggregation-Activity Relationship (QAAR): Supermolecular View, Dimer as the Simplest Aggregation State and Monomolecule”, QSAR Com. Sci. 2007, 26, 737-743

5.  Yanli Wang, Jiagao Cheng, Xuhong Qian*, Zhong Li*, “Actions between neonicotinoids and key residues of insect nAChR based on an ab initio quantum chemistry study: Hydrogen bonding and    cooperative p-p interaction”, Bioorg. Med. Chem. 2007, 15, 2624-2630

6. Feng Li, Jingnan Cui,* Lianying Guo, Xuhong Qian,*  Weimin Ren, Kewei Wang, Fengyu Liu, “Molecular design, chemical synthesis, and biological evaluation of ‘4-1’ pentacyclic arylimidazonaphthalimides”, Bioorg. Med. Chem. 2007, 15, 5114-5121

7. Chunliang Lu, Zhaochao Xu, Jingnan Cui,* Rong Zhang, Xuhong Qian*, “A Ratiometric and Highly Selective Fluorescent Sensor for Cadmium under Physiological pH Range: a New Strategy to Discriminate Cadmium from Zinc”, J. Org. Chem. 2007, 72, 3554-3557

8. Xuhong Qian*, Zhigang Li, Qing Yang*, “Highly efficient antitumor agents of heterocycles containing sulfur atom: Linear and angular thiazonaphthalimides against human lung cancer cell in vitro”, Bioorg. Med. Chem. 2007, 15, 6846-6851

9. Ming-Yi Cai, Xiao-Yong Xu,* Hou-Ju Li, Zhu-Yan Zou and Lu Li, 1-[(6-Chloropyridin-3-yl) methyl]-4-[2,6-dinitro-4-(trifluoromethyl)phenyl]-piperazine, Acta Crystallogr. E, 2007, E63, o3008

10. Xing Yong Wang, Jing Nan Cui*, Wei Min Ren, Feng Li, Chun Liang Lu, Xu Hong Qian*, “Baker’s yeast mediated reduction of substituted acenaphthenequinones: Regio- and enantioselective preparation of mono-hydroxyacenaphthenones”, Chinese Chem. Lett. 2007, 18, 681–684

11. Yufang Xu, Xuhong Qian, et al., Novel N-oxide of naphthalimides as prodrug leads against hypoxic solid tumor: Synthesis and biological evaluation, Bioorg. Med. Chem. Lett. 2007,17, 2166-2170

12. Yufang Xu, Xuhong Qian, et al., Novel cyanine dyes as fluorescent pH sensors: PET, ICT mechanism or resonance effect?, J. Photochem. Photobio A: Chem, 2007, 190, 1-8

13. Xuhong Qian, et al., Novel Bcl-2 Inhibitors: Discovery and Mechanism Study of Small Organic Apoptosis-Inducing Agents., Chembiochem, 2007, 8, 113-121

14. Xuhong Qian, et al., R16, a Novel Amonafide Analogue, Induces Apoptosis and G(2)-M Arrest via Poisoning Topoisomerase II., Mol. Cancer Ther., 2007, 6, 484-495

15. Yufang Xu, Xuhong Qian, et al., Novel Antitumor Agent Family of 1H-Benzo[c,d]Indol-2-One with Flexible Basic Side Chains: Synthesis and Biological Evaluation., Bioorg. Med. Chem., 2007, 15, 1356-1362

16. Qingchun Huang, Zhenhua Tang, et al., Fipronil resistance mechanisms in the rice stem borer, Chilo suppressalis Walker, Pestic. Biochem. Phys., 2007, 89, 169-174

17. Qingchun Huang, et al., Surfactant effect on persistence of oxadiazolyl 3(2H)-pyridazinones against Pseudaletia separata walker, J. Environ. SCI Heal. B, 2007, 42, 305-310

18. Yanqing Peng, Gonghua Song, et al., Amino-functionalized ionic liquid as catalytically active solvent for microwave-assisted synthesis of 4H-pyrans, Catal. Commun., 2007, 8, 111-114

19. Xuhong Qian, et al., A naphthalimide-calixarene as a two-faced and highly selective fluorescent chemosensor for Cu2+ or F-, Tetrahedron. Lett. 2007,: 48, 9151-9154



1.   Feng Li, Jingnan Cui,* Xuhong Qian,* Weimin Ren, Xingyong Wang“Baker’s yeast-mediated enantioselective reduction of substituted fluorenones”. Chem. Commun. 2006, 865-867.

2.  Yanming Ma, Runhui Liu, Xiuying Gong, Zhong Li,* Qingchun Huang, Haishui Wang, and Gonghua Song*, “Synthesis and Herbicidal Activity of  N,N-Diethyl-3-(arylselenonyl)-1H-1,2,4 triazole-1 –carboxamide”, J. Agric. Food Chem. 2006, 54, 7724- 7728

3.  Gangyue Li, Xuhong Qian,* Jingnan Cui, Qingchun Huang, Rong Zhang, Huai Guan, “Synthesis and herbicidal activity of novel 3-aminocarbonyl-2-oxazolidinethione derivatives containing a substituted pyridine ring”, J. Agric. Food Chem. 2006, 54, 125-129

4. Gangyue Li, Xuhong Qian,* Jingnan Cui, Qingchun Huang, Dawei Cui, Rong Zhang, Fengyu Liu, “Synthesis and herbicidal activities of fluorine-containing 3-pyridylmethyl-2-phenyliminothiazolidine derivatives”J. Fluor. Chem. 2006, 127, 182-186.

5. Zhongzhen Tian, Zhong Li*, Qingchun Huang, Xiaoyong Xu, Tao Yu, Yingli Wu, Xuhong Qian*, “Synthesis and Bioactivities of Novel Neonicotinoids Dioxolane Compounds”, J. Chem. Res(s). 2006, 626-628

6. Song Cao*, De-Li Lu, Chuan-Meng Zhao, Li-Na Li, Qing-Chun Huang, and Xu-Hong Qian*, “An Efficient and Practical Method for the Synthesis of 1-(2,6-Difluorobenzoyl)-3-[2’-alkyl-3’-oxopyridazin -4’-yl]ureas as Potential Chitin Synthesis Inhibitors”, Monatsh. Chem. 2006, 137, 779-784

7. Jiaobing Wang, Xuhong Qian*, “A series of polyamide receptor based PET fluorescent sensor molecules: positively cooperative Hg2+ ion binding with high sensitivity”, Org. Lett. 2006, 8, 3721-3724.

8. Zhaochao Xu, Xuhong Qian,* Jingnan Cui,* Rong Zhang “Exploiting the deprotonation mechanism for the design of ratiometric and colorimetric Zn2+ fluorescent chemosensor with a large red-shift in emission”, Tetrahedron, 2006, 62, 10117-10122

9. Jiaobing Wang, Xuhong Qian,* Jingnan Cui, “Detecting Hg2+ ions with an ICT fluorescent sensor molecule: Remarkable emission spectra shift and unique selectivity”, J. Org. Chem. 2006, 71, 4308-4311

10. Fengyu Liu, Xuhong Qian,* Jingnan Cui, Yi Xiao, Rong Zhang, Gangyue Li, “Design, synthesis, and antitumor evaluation of novel acenaphtho[1,2-b]pyrrole-carboxylic acid esters with amino chain substitution”, Bioorg. Med. Chem. 2006, 14, 4639-4644

11. Peng Yang, Qing Yang, Xuhong Qian*, Lianpeng Tong, Xiaolian Li, “Isoquino[4,5-bc]acridines: Design, synthesis and evaluation of DNA binding, anti-tumor and DNA photo-damaging ability”, J. Photoch. Photobio. B 2006, 84, 221-226

12. Qing Yang*, Jianqiang Xu, Xuhong Qian*, Kun Zhang, Xuyu Lei, “Eliminating nucleic acids contaminants by hydrogen peroxide-induced free radicals during the preparation of proteins”, Biochem. Eng. J. 2006, 29, 23-26

13. Qing Yang*, Jianqiang Xu, Yuanshe Sun, Zhigang Li, Yonggang Li, Xuhong Qian*, “Hydrolysis of plasmid DNA and RNA by amino alkyl naphthalimide as metal-free artificial nuclease”, Bioorg. Med. Chem. Lett. 2006, 16, 803-806

14. Mingyi Cai, Zhong Li*, Gonghua Song, 1-(6-Chloropyridin-3-ylmethyl)-1H-benzimidazole, Acta Crystallogr. E, 2006, E62, o2374

15. Xuhong Qian, et al., Two Regioisomeric and Exclusively Selective Hg(II) Sensor Molecules Composed of a Naphthalimide Fluorophore and an o-Phenylenediamine Derived Triamide Receptor., Chem. Commun., 2006, 109-111

16. Xuhong Qian, et al., Hydrolysis of Plasmid DNA and RNA by Amino Alkyl Naphthalimide as Metal-free Artificial Nuclease., Bioorg. Med. Chem. Lett., 2006, 16, 803-806

17. Xuhong  Qian, et al., Novel Fluorescent Markers for Hypoxic Cells of Naphthalimides with two Heterocyclic Side Chains for Bioreductive Binding, Bioorg. Med. Chem., 2006, 14, 2935-2941

18. Xuhong Qian, et al., Acenaphtho[1,2-b]Pyrrole Derivatives as New Family of Intercalators: Various DNA Binding Geometry and Interesting Antitumor Capacity., Bioorg. Med. Chem., 2006, 14, 6962-6970

19. Yanqing Peng, Gonghua Song, et al., Carboxyl-Functional Ionic Liquids as Scavengers: Case Studies on Benzyl Chloride, Amines and Methanesulfonyl Chloride, J. Comb. Chem., 2006, 8, 636-638

20. Yanqing Peng, Gonghua Song, et al., Surface cleaning under combined microwave and ultrasound irradiation: flash synthesis of 4H-pyrano[2,3-c]pyrazoles in aqueous media, Green Chem., 2006, 8, 573- 575

21. Yanqing Peng, Gonghua Song, et al., Amino-functionalized ionic liquid as an efficient and recyclable catalyst for Knoevenagel reactions in water, Catal. Lett., 2006, 109, 61- 64

22. Yufang Xu, Xuhong Qian, et al., Novel, Unnatural Benzo-1,2,3- thiadiazole-7-carboxylate Elicitors of Taxoid Biosynthesis, J. Agric. Food Chem., 2006, 54, 8793-8798

23. Yufang Xu, Xuhong Qian, et al., Synthesis and evaluation of novel 8-oxo-8H-cyclopenta[a]acenaphthylene-7-carbonitriles as long-wavelength fluorescent markers for hypoxic cells in solid tumor, Bioorg. Med. Chem. Lett. 2006,16, 1562-1566

24. Zhong Li, Qingchun Huang, Xuhong Qian, et al., Synthesis and bioactivities of novel neonicotinoids dioxolane compounds, J. Chem. Res. (S) 2006, 626



1. Feng Li, Jingnan Cui,* Xuhong Qian,* Rong Zhang, Yi Xiao“Highly chemoselective reduction of aromatic nitro compounds to the corresponding hydroxylamines catalysed by plant cells from grape (Vitis vinifera L.)”.  Chem. Commun. 2005, 1901-1903.

2. Song Cao*, Na Wei, Chuanmeng Zhao, Lina Li, Qingchun Huang, and Xuhong Qian*, “Syntheses, Antifeedants and QSAR Analysis of New Oxa(thia)diazolyl 3(2H)-Pyridazinones”, J. Agric. Food Chem. 2005, 53, 3120-3125

3. Chuanxiang Liu, Xiaoyong Xu, Zhong Li*, “Synthesis and biological activities of hydroxyl-protected fluorine-containing 4,4-dihydroxylmethyl-2-aryl-iminothiazolidines”, J. Fluorine Chem. 2005, 12653-58

4. Zhong Li*, Xiaoyong Xu, Yanqing Peng, Zhaoxing Jiang, Chuanyong Ding, Xuhong Qian, “An Unusual Synthesis of Tröger’s Bases Using DMSO/HCl(g) as Formaldehyde Equivalent”, Synthesis 2005, 1228-1230

5. Zhaochao Xu, Xuhong Qian*, Jingnan Cui*, “A Colorimetric and Ratiometric Fluorescent Chemosensor With a Large Red-shift in Emission: Cu(II)-Only Sensing by Deprotonation of Secondary Amines as Receptor Conjugated to Naphthalimide Fluorophore”, Org. Lett. 2005, 7, 3029-3032.

6. Zhaochao Xu, Yi Xiao, Xuhong Qian*, Jingnan Cui*, Dawei Cui, “A Ratiometric and Selective Fluorescent Sensor for Cu Based on Internal Charge Transfer (ICT)”, Org. Lett. 2005, 7, 889-892.

7. Fengyu Liu, Yi Xiao, Xuhong Qian,* Zhichao Zhang, Jingnan Cui, Dawei Cui, Rong Zhang, “Versatile acenaphtho[1,2-b]pyrrol-carbonitriles as a new family of heterocycles: diverse SNArH reaction, cytotoxicity and spectral behavior”, Tetrahedron, 2005, 61, 11264-11269.

8. Yi, Xiao,* Meiyan Fu, Xuhong Qian*, Jingnan Cui, “A proton sponge-based fluorescent switch”, Tetrahedron Lett. 2005, 46, 6289-6292.

9. Peng Yang, Qing Yang, Xuhong Qian,* Jingnan Cui, “Novel synthetic isoquinolino[5,4-ab]phenazines: inhibition toward topoisomerase I, antitumor and DNA photo-cleaving activities”, Bioorg. Med. Chem. 2005, 13, 5909-5914.

10. Peng Yang, Qing Yang, Xuhong Qian*, “Novel DNA bis-intercalators of isoquinolino[4,5-bc]acridines: design, synthesis and evaluation of cytotoxic activity”, Tetrahedron, 2005, 61, 11895-11901

12. Zhigang Li, Qing Yang, Xuhong Qian*, “Synthesis, antitumor and DNA photocleaving activities of novel naphthalene carboxamides: effects of different thio-heterocyclic rings and aminoalkyl side chains”. Tetrahedron, 2005, 61, 8711-8717

13. Zhigang Li, Qing Yang, Xuhong Qian*, “Novel thiazonaphthalimides as efficient antitumor and DNA photocleaving agents: Effects of intercalation, side chains, and substituent groups”, Bioorg. Med. Chem. 2005, 13, 4864-4870

14. Zhigang Li, Qing Yang, Xuhong Qian*, “Synthesis of thiazo- or thiadiazo- naphthalene carboxamides via mercuric intermediates and their antitumor and DNA photocleavage activities”. Tetrahedron, 2005, 61, 6634-6641

15. Zhigang Li, Qing Yang, Xuhong Qian*, “Synthesis, antitumor evaluation and DNA photocleaving activity of novel methylthiazonaphthalimides with aminoalkyl side chains”. Bioorg. Med. Chem. Lett., 2005, 15, 3143-3146

16. Zhigang Li, Qing Yang, Xuhong Qian*, “Novel heterocyclic family of phenyl naphthothiazole carboxamides derived from naphthalimides: synthesis, antitumor evaluation, and DNA photocleavage”. Bioorg. Med. Chem. 2005, 13, 3149-3155

17. Zhigang Li, Qing Yang, Xuhong Qian*, “Novel 2-aminothiazonaphthalimides as visible light activatable photonucleases: effects of intercalation, heterocyclic-fused area and side chains”, Bioorg. Med. Chem. Lett. 2005, 15, 1769-1772

18. Qing Yang*, Xuhong Qian*, Jianqiang Xu, Yuanshe Sun, Yonggang Li, “Thio-heterocylic naphthalimides with aminoalkyl side chains: novel alternative tools for photodegradation of genomic DNA without impairment on bioactivities of proteins”. Bioorg. Med. Chem. 2005, 13, 1615-1622

19. Xuhong Qian, et al., A pH-Resistant Zn(II) Sensor Drived from 4-Aminonaphthalimide: Design, Synthesis and Intracellular Applications., J. Mater. Chem., 2005, 15, 2836-2839

20. Xuhong Qian, et al., Visible Study of Mercuric Ion and its Conjugate in Living Cells of Mammals and Plants, Chem. Res. Toxicol., 2005,  18,1814-1820

21. Xuhong Qian, et al., A New Class of Long-Wavelength Fluorophores: Strong Red Fluorescence,Convenient Synthesis and Easy Derivation., Chem. Commun., 2005, 239-241

22. Yufang Xu, Xuhong Qian, et al., Five-member thio-Heterocyclic Fused Naphthalimides with Aminoalkyl Side Chains: Intercalation and Photocleavage to DNA., Bioorg. Med. Chem. Lett., 2005, 15, 1139-1142

23. Yanqing Peng, Gonghua Song, et al., Solution phase parallel synthesis of 4-amino phenyl ethers using a carboxyl-functionalized ionic liquid as support, Monatsh. Chem., 2005, 136, 1751-1755

24. Yanqing Peng, Gonghua Song, et al., Ionic liquid-grafted Mn(III)-Schiff base complex: A highly efficient and recyclable catalyst for the epoxidation of chalcones, Synlett., 2005, 2147-2150

25. Yanqing Peng, Gonghua Song., et al., Dramatically accelerated synthesis of β-amino- ketones via aqueous Mannich reaction under combined microwave and ultrasound irradiation, Synlett., 2005, 2245-2247

26. Gonghua Song, Yanqing Peng, et al., Amino-functionalized Ionic Liquid as a Nucleophilic Scavenger in Solution Phase Combinatorial Synthesis, J. Comb. Chem., 2005, 7, 561-566

27. Yanqing Peng, Gonghua Song, et al., Mannich reaction catalyzed by carboxyl-functionalized ionic liquid in aqueous media, Catal. Lett., 2005, 102, 159-162

28. Yanqing Peng, Gonghua Song, et al., Solid phase synthesis of aminochalcones, J. Chem. Res. (S), 2005, 311-312

29. Yanqing Peng, Gonghua Song, et al., Tetramethylguanidine-[bmim][BF4].An efficient and recyclahle catalytic system for one-pot synthesis of 4H-pyrans. Monatsh. Chem., 2005, 136, 727-731

30. Yanqing Peng, Gonghua Song, et al., Microwave-assisted liquid-phase synthesis of methyl 6-amino-5- cyano-4-aryl-2-methyl- 4H-pyran-3- carboxylate using functional ionic liquid as soluble support, Tetrahedron Lett., 2005,  46, 3931-3933

31. Yanqing Peng, Gonghua Song, et al., Efficient and mild room temperature reduction of benzophenones under ultrasound irradiation, Ultrasonics Sonochem., 2005, 12, 169-172

32. Yufang Xu, Xuhong Qian, et al., A novel synthetic fluoro-containing jasmonate derivative acts as a chemical inducing signal for plant secondary metabolism, Appl. Microbio. Biotech. 2005, 68, 98

33. Xuhong Qian, et al., A novel photocleaver with long wavelength absorption - Highly efficient antitumor agent: 4-(2-diethylamino-ethylamino)-8-oxo-8H-acenaphtho-[1,2-b] pyrrole-9-carbonitrile, Chem. Res. Chin. Univ. 2005, 21, 4, 480



1. Feng Li, Jingnan Cui,* Xuhong Qian, Rong Zhang“A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers’ yeast”. Chem. Commun. 2004, 2338-2339.

2. Dawei Cui, Xuhong Qian,* Fengyu Liu, Rong Zhang, “Novel fluorescent pH sensors based on intramolecular hydrogen bonding ability of naphthalimide”. Org. Lett. 2004, 6, 2757-2760

3. Xiaoyong Xu, Xuhong Qian*, Zhong Li, Gonghua Song, Weidong Chen, “Synthesis and fungicidal activity of fluorine-containing phenyliminothiazolidines derivatives”, J. Fluorine Chem. 2004, 1251159-1162

4. Xuhong Qian*, Xiaoyong Xu, Zhibin Li, Zhong Li, Gonghua Song, “Syntheses, Structures and Bioactivities of Fluorine-containing Phenylimino-thia(oxa)zolidine Derivatives as Agricultural Bioregulators”, J. Fluorine Chem. 2004, 125, 1609-1620.

5. Xuhong Qian, et al., A Highly Selective and Sensitive Fluorescent Chemosensor for Hg2+ in Neutral Buffer Aqueous Solution, J. Am. Chem. Soc., 2004, 126, 2272-2273

6. Xuhong Qian, et al., A Novel Chromatism Switcher with Double Receptors Selectively for Ag+ in Neutral Aqueous Solution: 4,5-Diaminoalkeneamino -N-Alkyl-1,8-Naphthalimides, Tetrahed. Lett., 2004, 45, 3969-3973

7. Xuhong Qian, et al., Fluorescent Imaging of Acute Mercuric Chloride Exposure on Cultured Human Kidney Tubular Epithelial Cells, Kidney Int., 2004, 66, 2279-2282

8. Xuhong Qian, et al., Highly-Efficient DNA Photocleavers with Long Wavelength Absorptions: Thio- Heterocyclic Fused Naphthalimides Containing Aminoalkyl Side Chains, Bioorg. Med. Chem. Lett., 2004, 14, 2665-2668

9. Xuhong Qian, et al., Naphthalimide-thiazoles as Novel Photonucleases: Molecular Design, Synthesis, and Evaluation, Tetrahed. Lett., 2004, 45, 1247-1251

10. Xuhong Qian, et al., N-Aroyloxylthioxo-Naphthalimides as DNA Photocleavers of Aroyloxyl Oxygen Radicals: Synthesis, Evaluation, and Substituents' Effect, Bioorg. Med. Chem., 2004, 12, 2335-2341

11. Yanqing Peng, Gonghua Song, et al., Microwave-assisted clean synthesis of 6-aryl-2,4-diamino- 1,3,5-triazines in [bmim][PF6], Tetrahedron Lett., 2004,  45, 5313-1316

12. Yanqing Peng, Gonghua Song, et al., One-pot three-step synthesis of 3-aryl-2-benzoylimino-4- thiazolidinones in the ionic liquid [bmim(+)][PF6-], J. Chem. Res. (S), 2004, 676-678

13. Yanqing Peng, Gonghua Song, et al., Bisacetamide hydrochloride: A chemoselective and inexpensive N-acetylating reagent for aminophenols, Indian J. Chem. B, 2004, 43B, 2021-2023

14. Yanqing Peng, Gonghua Song, Xiaoyong Xu, et al., Ultrasound-promoted scavenging: a rapid parallel purification for solution phase combinatorial synthesis, J. Chem. Res. (S), 2004, 261-263

15. Yufang Xu, Xuhong Qian, et al., Novel fluoro- and hydroxyl- containing jasmonate derivatives as highly efficient elicitors in suspension cultures of Taxus chinensis, Bioorg. Med. Chem. Lett., 2004, 14, 4755

16. Xuhong Qian, et al., Novel Synthetic Jasmonates as Highly Efficient Elicitors for Taxoid Production by Suspension Cultures of Taxus chinensis, Biotechnol. Bioeng., 2004, 86, 595

17. Xuhong Qian, et al., Benzothioxanthene dyes as fluorescent label for DNA hybridization: synthesis and application, Dyes Pigments, 2004, 60, 9

18. Xuhong Qian, et al., Synthesis and peroxidase-staining properties of novel water soluble polyhydroxylalkyl benzidine dyes, Dyes Pigments2004, 60, 17

19. Yanqing Peng, Gonghua Song, et al., Synthesis of 3-substituted-2-acylimino-4-thiazo lidones under microwave irradiation, Org. Prep. Proc. Int. 2004, 35, 151

20. Xuhong Qian, Qingchun Huang, et al., Novel analogues of alpha-terthienyl, thienyl 1,3,4-thia(oxa)diazoles as potential photoactivated insecticides: Synthesis and bioactivity, Chin. Chem. Lett. 2004, 15, 7